STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2VMF5_NAEGRDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (350 aa)    
Predicted Functional Partners:
D2VJ07_NAEGR
Deoxyhypusine synthase.
   
 0.922
D2V8F6_NAEGR
Predicted protein.
  
 0.867
D2V8H5_NAEGR
Eukaryotic translation initiation factor 5A.
  
 0.867
D2VEX0_NAEGR
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
  
 0.867
D2VGA4_NAEGR
Predicted protein.
  
 0.846
D2V6Q8_NAEGR
Predicted protein; Belongs to the cullin family.
      
 0.728
D2VTI3_NAEGR
Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.
   
    0.719
D2UXU6_NAEGR
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
    0.693
D2V0N5_NAEGR
Predicted protein.
   
    0.676
D2VG52_NAEGR
Predicted protein.
   
    0.676
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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