STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2W6H5_NAEGRWD40 repeat domain-containing protein. (113 aa)    
Predicted Functional Partners:
D2VJJ6_NAEGR
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.844
D2V7J7_NAEGR
Actin-related protein ARP3; Belongs to the actin family.
   
 0.713
D2VPR0_NAEGR
Actin-related protein ARP3; Belongs to the actin family.
   
 0.713
D2VKI4_NAEGR
Predicted protein.
   
 
 0.669
D2VP99_NAEGR
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 
  0.601
D2V9N2_NAEGR
Actin related protein 2; Belongs to the actin family.
   
 0.570
D2VJG9_NAEGR
Actin related protein; Belongs to the actin family.
   
 0.570
D2VIP0_NAEGR
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.564
D2V084_NAEGR
Predicted protein.
   
 
 0.562
D2V1W7_NAEGR
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.562
Your Current Organism:
Naegleria gruberi
NCBI taxonomy Id: 5762
Other names: N. gruberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.