STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F0ZSA2_DICPUThymidine kinase. (234 aa)    
Predicted Functional Partners:
F0ZQ28_DICPU
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.988
F0ZE99_DICPU
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.984
F0ZHC0_DICPU
Thymidylate_kin domain-containing protein.
  
 
 0.981
F0ZQC1_DICPU
Thymidylate kinase.
  
 
 0.981
F0ZQA7_DICPU
dUTPase domain-containing protein.
  
 
 0.971
F0ZVX1_DICPU
dUTPase domain-containing protein.
  
 
 0.971
F0ZLC4_DICPU
PNP_UDP_1 domain-containing protein.
     
 0.933
F0ZNG7_DICPU
Uridine phosphorylase.
     
 0.933
F0ZSE1_DICPU
DHFR domain-containing protein.
  
 
 0.915
F0ZUT3_DICPU
5'-nucleotidase.
     
  0.900
Your Current Organism:
Dictyostelium purpureum
NCBI taxonomy Id: 5786
Other names: D. purpureum
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