STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)    
Predicted Functional Partners:
udk
TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: esa:ESA_01152 uridine kinase.
  
 0.979
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.965
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
 
 0.961
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.943
ACS84588.1
Cytosine deaminase; PFAM: Amidohydrolase 3; amidohydrolase; KEGG: esa:ESA_03405 hypothetical protein.
  
 
 0.941
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.938
ACS83864.1
KEGG: aav:Aave_0967 dihydropyrimidine dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
   
 
 0.927
ACS84005.1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.921
ACS85937.1
TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: kpe:KPK_3428 ribose 5-phosphate isomerase B.
 
  
 0.909
deoD
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eta:ETA_06690 purine nucleoside phosphorylase DeoD-type.
    
 0.909
Your Current Organism:
Dickeya paradisiaca
NCBI taxonomy Id: 579405
Other names: D. paradisiaca Ech703, Dickeya dadantii Ech703, Dickeya paradisiaca Ech703
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.