STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS85184.1PFAM: major facilitator superfamily MFS_1; KEGG: sew:SeSA_A1457 inner membrane transport protein YdiM. (413 aa)    
Predicted Functional Partners:
ydiB
Shikimate dehydrogenase substrate binding domain protein; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
 
     0.758
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
     0.755
ACS85185.1
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpe:KPK_4670 transcriptional regulator, LysR family.
  
    0.625
ACS85938.1
PFAM: PTS system glucitol/sorbitol-specific IIA component; KEGG: kpn:KPN_01124 PTS family enzyme IIA, glucitol/sorbitol-specific.
  
     0.600
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
  
     0.425
ACS87238.1
PFAM: protein of unknown function DUF1440; KEGG: cje:Cj0014c putative integral membrane protein.
  
     0.423
Your Current Organism:
Dickeya paradisiaca
NCBI taxonomy Id: 579405
Other names: D. paradisiaca Ech703, Dickeya dadantii Ech703, Dickeya paradisiaca Ech703
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