STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (319 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.990
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.985
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
  
 0.957
Tlie_1283
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.944
Tlie_1222
PFAM: D-ala D-ala ligase C-terminus; COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761; KEGG: aco:Amico_0187 D-alanine--D-alanine ligase; SPTR: Putative D-ala D-ala ligase domain protein.
  
  
 
0.929
Tlie_1220
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 
0.928
Tlie_0586
PFAM: OstA-like protein; COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR005653; KEGG: aco:Amico_1470 OstA family protein; PFAM: OstA family protein; SPTR: OstA family protein.
     
 0.841
Tlie_0978
Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR004276: IPR007235; KEGG: aco:Amico_0819 undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR: Putative UDP-N-acetylglucosamine--N- [...]
 
  
 0.818
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.793
Tlie_0585
PFAM: Protein of unknown function (DUF1239); KEGG: aco:Amico_1471 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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