STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proRSProline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity). Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has no activity on correctly charged Pro- tRNA(Pro) or Ala-tRNA(Ala). (746 aa)    
Predicted Functional Partners:
PF3D7_1349200
Glutamate--tRNA ligase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.987
PF3D7_0622800
Leucine--tRNA ligase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.986
PF3D7_1332900
Isoleucine--tRNA ligase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.983
PF3D7_0925300
Proline--tRNA ligase, putative.
    
0.960
PF3D7_0102900
Aspartate--tRNA ligase.
  
 0.957
PF3D7_0828200
Leucine--tRNA ligase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.950
PF3D7_1331700
Glutamine--tRNA ligase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.942
PF3D7_1225100
Isoleucine--tRNA ligase, putative.
   
 
 0.938
PF3D7_1218600
Arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.935
PF3D7_1350100
Lysine--tRNA ligase.
  
 
 0.924
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.