STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igag_0904COGs: COG1874 Beta-galactosidase; InterPro IPR001944:IPR013529:IPR002345; KEGG: cma:Cmaq_0900 beta-galactosidase; PFAM: glycoside hydrolase family 35; Glycoside hydrolase family 42 domain protein; PRIAM: Beta-galactosidase; SPTR: A8MD78 Beta-galactosidase; PFAM: Glycosyl hydrolases family 35; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type. (902 aa)    
Predicted Functional Partners:
Igag_0371
Beta-glucuronidase; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101:IPR006104:IPR006102:IPR006103; KEGG: sso:SSO3036 beta-glucuronidase (GusB); PFAM: glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; PRIAM: Beta-glucuronidase; SPTR: Q97UI1 Beta-glucuronidase (GusB); PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain.
 
 
 0.624
Igag_1033
COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933; KEGG: sim:M1627_2379 alpha-L-fucosidase; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); PRIAM: Alpha-L-fucosidase; SPTR: C3N1K9 Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase.
  
   
 0.564
Igag_0903
AAA ATPase; InterPro IPR003593; KEGG: pab:PAB0810 hypothetical protein; SMART: AAA ATPase; SPTR: O29202 Putative uncharacterized protein; PFAM: Domain of unknown function DUF87.
 
     0.555
Igag_0310
COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sso:SSO3022 alpha-xylosidase (XylS); PFAM: glycoside hydrolase family 31; PRIAM: Alpha-glucosidase; SPTR: Q9P999 Alpha-xylosidase; PFAM: Glycosyl hydrolases family 31; Belongs to the glycosyl hydrolase 31 family.
 
  
 0.547
Igag_0902
NurA domain; InterPro IPR018977; KEGG: tne:Tneu_1343 hypothetical protein; PFAM: NurA domain; PFAM: NurA domain.
       0.494
Igag_1847
GHMP kinase; COGs: COG0153 Galactokinase; InterProIPR006206:IPR000705:IPR001174:IPR013750:IPR 006204:IPR006203; KEGG: dka:DKAM_0259 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: B8D2K4 GHMP kinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: mevalonate kinase.
 
  
 0.491
Igag_0906
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644:IPR002932; KEGG: cma:Cmaq_1624 malate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; ferredoxin-dependent glutamate synthase; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: A8M9X6 Malate dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase.
     
 0.467
ade
COGs: COG1001 Adenine deaminase; InterPro IPR006680:IPR019775; KEGG: smr:Smar_0382 adenine deaminase; PFAM: amidohydrolase; PRIAM: Adenine deaminase; SPTR: A3DLI4 Adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.459
Your Current Organism:
Ignisphaera aggregans
NCBI taxonomy Id: 583356
Other names: I. aggregans DSM 17230, Ignisphaera aggregans DSM 17230, Ignisphaera aggregans str. DSM 17230, Ignisphaera aggregans strain DSM 17230
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.