STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoyl synthase, apicoplast; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (442 aa)    
Predicted Functional Partners:
PKH_141370
Lipoate-protein ligase 1, putative.
 
 
 0.993
PKH_093070
Glycine cleavage system H protein, putative.
   
 0.983
PKH_072080
Lipoate-protein ligase 2, putative.
  
 
 0.981
PKH_050740
Lipoate-protein ligase B, putative.
 
 
 0.927
PKH_145600
Hydrolase, putative.
    
 0.772
PKH_041360
Pantothenate transporter, putative.
     
 0.685
PKH_061930
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
  
 0.662
PKH_121240
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
  
 0.648
PKH_131210
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
      0.648
PKH_141280
Septum formation protein MAF homologue,putative.
   
  
 0.627
Your Current Organism:
Plasmodium knowlesi
NCBI taxonomy Id: 5851
Other names: P. knowlesi strain H, Plasmodium knowlesi (STRAIN H), Plasmodium knowlesi H, Plasmodium knowlesi Malayan H, Plasmodium knowlesi strain H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.