STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKH_125100Hemolysin, putative. (264 aa)    
Predicted Functional Partners:
PKH_073030
Protein MAM3, putative.
     
 0.649
PKH_082480
Transporter, putative.
    
 
 0.632
PKH_093060
Aquaglyceroporin, putative; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.598
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
      
 0.512
PKH_120260
Uncharacterized protein.
   
 0.508
PKH_124290
Glyceraldehyde-3-phosphate dehydrogenase.
   
  
 0.507
PKH_120680
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
  
 0.506
PKH_146430
RAC-beta serine/threonine protein kinase,putative.
   
 0.504
PKH_041690
Repetitive organellar protein, putative.
  
 0.500
PKH_091870
Tyrosine kinase-like protein, putative.
  
 0.500
Your Current Organism:
Plasmodium knowlesi
NCBI taxonomy Id: 5851
Other names: P. knowlesi strain H, Plasmodium knowlesi (STRAIN H), Plasmodium knowlesi H, Plasmodium knowlesi Malayan H, Plasmodium knowlesi strain H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.