STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaEBeta-ketoadipyl CoA thiolase; Catalyzes thiolytic cleavage of beta-ketoadipyl-CoA to succinyl-CoA and acetyl-CoA. (401 aa)    
Predicted Functional Partners:
paaH
3-hydroxybutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied species; enzyme.
 0.999
paaF
enoyl-CoA hydratase-isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.998
paaG
acyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme.
 
 0.998
maoC
Fused aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme.
 
 0.994
CAQ98345.1
Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 0.982
paaK
phenylacetyl-CoA ligase; Function experimentally demonstrated in the studied species; enzyme.
  
  
 0.972
fadB
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 0.971
yfcX
Fused enoyl-CoA hydratase and epimerase and isomerase; Function experimentally demonstrated in the studied species; enzyme.
 0.970
paaB
Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.956
paaC
Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.951
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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