STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PVX_100730Serine hydroxymethyltransferase, putative. (442 aa)    
Predicted Functional Partners:
PVX_089950
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.981
PVX_092250
Lipoyl-binding domain-containing protein.
  
 
 0.966
PVX_115235
Aminomethyltransferase, mitochondrial, putative.
  
 0.962
PVX_122485
Formyl transferase domain containing protein.
     
 0.935
PVX_101195
5-aminolevulinic acid synthase, putative.
  
 
 0.933
PVX_089610
Dihydrolipoamide dehydrogenase, putative; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.923
PVX_100555
Dihydrolipoyl dehydrogenase.
  
 
 0.923
PVX_117660
Serine hydroxymethyltransferase, putative.
  
  
 
0.913
PVX_003765
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.855
PVX_114710
Adenylosuccinate synthetase; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
  
  
 0.785
Your Current Organism:
Plasmodium vivax
NCBI taxonomy Id: 126793
Other names: P. vivax Sal-1, Plasmodium vivax (STRAIN SAL-I), Plasmodium vivax (strain Salvador I), Plasmodium vivax SaI-1, Plasmodium vivax Sal-1, Plasmodium vivax Salvador I
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