STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PVX_111005Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (633 aa)    
Predicted Functional Partners:
PVX_123345
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
 0.999
PVX_084960
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.995
PVX_099805
Fumarate hydratase, putative.
  
 
 0.984
PVX_091100
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.982
PVX_118520
Ubiquinol cytochrome c oxidoreductase, putative.
  
 
 0.972
PVX_089325
2-oxoglutarate dehydrogenase E1 component, mitochondrial, putative.
  
 
 0.972
PVX_117325
Cytochrome c1, putative.
   
 
 0.941
PVX_003655
Aspartate aminotransferase.
   
 0.922
PVX_002685
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
  
 0.915
PVX_094390
U5 small nuclear ribonuclear protein, putative.
  
 
 0.881
Your Current Organism:
Plasmodium vivax
NCBI taxonomy Id: 126793
Other names: P. vivax Sal-1, Plasmodium vivax (STRAIN SAL-I), Plasmodium vivax (strain Salvador I), Plasmodium vivax SaI-1, Plasmodium vivax Sal-1, Plasmodium vivax Salvador I
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