STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (341 aa)    
Predicted Functional Partners:
selA
L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.998
selB
Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09107; InterPro: IPR004535.
 
   
 0.959
iscS
Aminotransferase, class V; COG: COG1104; Pfam: PF00266; InterPro: IPR000192.
   
 0.919
sufS
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
   
 0.898
trxB
Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982.
     
 0.896
thiF
Molybdopterin biosynthesis protein MoeB; COG: COG0476; Pfam: PF00899,PF05237,PF00581; InterPro: IPR016040.
   
 0.765
EFG48570.1
ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439.
       0.497
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
      
 0.453
fdnG
Molybdopterin oxidoreductase Fe4S4 domain protein; COG: COG0243; Pfam: PF04879; InterPro: IPR006963.
 
   
 0.429
EFG48632.1
Putative thioredoxin; COG: COG3118; Pfam: PF00085; InterPro: IPR012335.
     
 0.408
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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