STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG48437.1CoA-transferase family III protein; COG: COG1804; Pfam: PF02515; InterPro: IPR003673; Belongs to the CoA-transferase III family. (276 aa)    
Predicted Functional Partners:
EFG47454.1
MaoC-like protein; COG: COG2030; Pfam: PF01575; InterPro: IPR002539.
 
 
  0.648
menE2
AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873.
       0.639
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.626
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
  0.623
EFG48438.1
Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR012287.
 
     0.621
accD
Putative acetyl-CoA carboxylase, carboxyl transferase, beta subunit; COG: COG0777; Pfam: PF01039; InterPro: IPR000022.
    
  0.612
acdA2
acyl-CoA dehydrogenase, C-terminal domain protein; COG: COG1960; Pfam: PF02771,PF02770,PF00441; InterPro: IPR006090.
 
 
  0.525
fadB2x
Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  0.411
crt
enoyl-CoA hydratase/isomerase family protein; COG: COG1024; Pfam: PF00378; InterPro: IPR001753; Belongs to the enoyl-CoA hydratase/isomerase family.
  
    0.411
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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