STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG48348.1Hypothetical protein; Pfam: PF00440. (178 aa)    
Predicted Functional Partners:
EFG48347.1
Hypothetical protein.
       0.769
pafA
Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
     0.666
EFG47070.1
Proteasome accessory factor PafA2; Pfam: PF03316,PF03136; InterPro: IPR004347.
  
     0.609
EFG48350.1
UvrD/REP helicase; COG: COG0210; Pfam: PF00580; InterPro: IPR000212; Belongs to the helicase family. UvrD subfamily.
       0.568
cyaA
Adenylate/guanylate cyclase catalytic domain protein; Pfam: PF00211.
  
     0.550
arc
Proteasome ATPase; COG: COG0464; Pfam: PF00004; InterPro: IPR003959.
  
     0.547
EFG48349.1
Hypothetical protein; COG: COG2887.
       0.518
EFG47714.1
Putative ABC transporter; COG: COG0842; Pfam: PF01061.
  
     0.511
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.496
EFG47562.1
Hypothetical protein.
  
     0.470
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.