| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG48367.1 | argD | HMPREF0183_0335 | HMPREF0183_1147 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | 0.887 |
| EFG48367.1 | argG | HMPREF0183_0335 | HMPREF0183_1150 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.867 |
| EFG48367.1 | coaBC | HMPREF0183_0335 | HMPREF0183_1823 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.889 |
| EFG48367.1 | cysK | HMPREF0183_0335 | HMPREF0183_0133 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.871 |
| EFG48367.1 | dapD | HMPREF0183_0335 | HMPREF0183_0298 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.936 |
| EFG48367.1 | dapE | HMPREF0183_0335 | HMPREF0183_0299 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Succinyl-diaminopimelate desuccinylase; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010174. | 0.935 |
| EFG48367.1 | lysC | HMPREF0183_0335 | HMPREF0183_1195 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Aspartate kinase, monofunctional class; COG: COG0527; Pfam: PF00696,PF01842; InterPro: IPR005260; Belongs to the aspartokinase family. | 0.863 |
| EFG48367.1 | malY | HMPREF0183_0335 | HMPREF0183_0653 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR004839. | 0.861 |
| EFG48367.1 | metK | HMPREF0183_0335 | HMPREF0183_1824 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.871 |
| EFG48367.1 | sucA | HMPREF0183_0335 | HMPREF0183_0343 | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00198,PF00676,PF02779; InterPro: IPR011603. | 0.861 |
| argD | EFG48367.1 | HMPREF0183_1147 | HMPREF0183_0335 | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 0.887 |
| argD | argG | HMPREF0183_1147 | HMPREF0183_1150 | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.988 |
| argD | dapD | HMPREF0183_1147 | HMPREF0183_0298 | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.904 |
| argD | dapE | HMPREF0183_1147 | HMPREF0183_0299 | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | Succinyl-diaminopimelate desuccinylase; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010174. | 0.887 |
| argG | EFG48367.1 | HMPREF0183_1150 | HMPREF0183_0335 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 0.867 |
| argG | argD | HMPREF0183_1150 | HMPREF0183_1147 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636. | 0.988 |
| argG | dapE | HMPREF0183_1150 | HMPREF0183_0299 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Succinyl-diaminopimelate desuccinylase; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010174. | 0.884 |
| argG | lysC | HMPREF0183_1150 | HMPREF0183_1195 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate kinase, monofunctional class; COG: COG0527; Pfam: PF00696,PF01842; InterPro: IPR005260; Belongs to the aspartokinase family. | 0.915 |
| coaBC | EFG48367.1 | HMPREF0183_1823 | HMPREF0183_0335 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839. | 0.889 |
| coaBC | cysK | HMPREF0183_1823 | HMPREF0183_0133 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.894 |