STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pccB2Carboxyl transferase domain protein; COG: COG4799; Pfam: PF01039; InterPro: IPR000022. (531 aa)    
Predicted Functional Partners:
accA
Carbamoyl-phosphate synthase L chain, ATP binding domain protein; COG: COG4770; Pfam: PF00289,PF02786,PF02785,PF00364; InterPro: IPR013816.
 
 0.983
EFG48382.1
Hypothetical protein; Pfam: PF07287; InterPro: IPR010839; 3.6.1.11.
 
 
 0.917
EFG48385.1
enoyl-CoA hydratase/isomerase family protein; COG: COG1024; Pfam: PF00378; InterPro: IPR001753.
 
 
  0.883
accA2
Carbamoyl-phosphate synthase L chain, ATP binding domain protein; COG: COG4770; Pfam: PF00289,PF02786,PF02785,PF00364; InterPro: IPR013816.
 
 0.870
bccA
Putative acetyl-CoA carboxylase, biotin carboxylase subunit; COG: COG4770; Pfam: PF00289,PF02786,PF02785,PF00364; InterPro: IPR013816.
 
 0.866
accD
Putative acetyl-CoA carboxylase, carboxyl transferase, beta subunit; COG: COG0777; Pfam: PF01039; InterPro: IPR000022.
  
 
 0.852
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.770
mmsB
3-hydroxyisobutyrate dehydrogenase; COG: COG2084; Pfam: PF03446; InterPro: IPR011548.
  
 
  0.731
fabD
Putative [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227.
  
 
 0.714
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.712
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.