STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; COG: COG0502; Pfam: PF04055,PF06968; InterPro: IPR013785. (446 aa)    
Predicted Functional Partners:
birA
biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340; Pfam: PF03099,PF02237; InterPro: IPR004408.
  
 
 0.963
argD
Aminotransferase, acetylornithine/succinylornithine family; COG: COG4992; Pfam: PF00202; InterPro: IPR004636.
 
 
 
 0.587
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
      
 0.582
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.532
hemD
uroporphyrinogen-III synthase; COG: COG1587; Pfam: PF00590,PF02602; InterPro: IPR003754; Belongs to the precorrin methyltransferase family.
 
   
 0.529
tetR
Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR012287.
 
   
 0.514
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.498
carB
Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family.
  
 
 0.490
EFG48322.1
Hypothetical protein.
       0.484
EFG47549.1
TIGR03085 family protein.
  
  
  0.464
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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