| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG48059.1 | EFG48189.1 | HMPREF0183_0575 | HMPREF0183_0446 | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | 0.898 |
| EFG48059.1 | EFG48202.1 | HMPREF0183_0575 | HMPREF0183_0459 | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | DivIVA domain protein; Pfam: PF05103. | 0.913 |
| EFG48059.1 | ponA | HMPREF0183_0575 | HMPREF0183_1201 | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | 0.570 |
| EFG48136.1 | EFG48201.1 | HMPREF0183_0652 | HMPREF0183_0458 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; COG: COG0762. | 0.572 |
| EFG48136.1 | EFG48202.1 | HMPREF0183_0652 | HMPREF0183_0459 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | DivIVA domain protein; Pfam: PF05103. | 0.686 |
| EFG48136.1 | sepF | HMPREF0183_0652 | HMPREF0183_0457 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.860 |
| EFG48189.1 | EFG48059.1 | HMPREF0183_0446 | HMPREF0183_0575 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | 0.898 |
| EFG48189.1 | EFG48197.1 | HMPREF0183_0446 | HMPREF0183_0454 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Hypothetical protein. | 0.990 |
| EFG48189.1 | EFG48201.1 | HMPREF0183_0446 | HMPREF0183_0458 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Hypothetical protein; COG: COG0762. | 0.409 |
| EFG48189.1 | EFG48202.1 | HMPREF0183_0446 | HMPREF0183_0459 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | DivIVA domain protein; Pfam: PF05103. | 0.791 |
| EFG48189.1 | crgA | HMPREF0183_0446 | HMPREF0183_2241 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Hypothetical protein; Involved in cell division; Belongs to the CrgA family. | 0.822 |
| EFG48189.1 | dnaE2 | HMPREF0183_0446 | HMPREF0183_0462 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | DNA polymerase III, alpha subunit; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805. | 0.452 |
| EFG48189.1 | ftsZ | HMPREF0183_0446 | HMPREF0183_0455 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.925 |
| EFG48189.1 | ponA | HMPREF0183_0446 | HMPREF0183_1201 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Transglycosylase; COG: COG0744; Pfam: PF00912,PF00905; InterPro: IPR001460. | 0.892 |
| EFG48189.1 | sepF | HMPREF0183_0446 | HMPREF0183_0457 | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.693 |
| EFG48197.1 | EFG48189.1 | HMPREF0183_0454 | HMPREF0183_0446 | Hypothetical protein. | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | 0.990 |
| EFG48197.1 | EFG48201.1 | HMPREF0183_0454 | HMPREF0183_0458 | Hypothetical protein. | Hypothetical protein; COG: COG0762. | 0.479 |
| EFG48197.1 | EFG48202.1 | HMPREF0183_0454 | HMPREF0183_0459 | Hypothetical protein. | DivIVA domain protein; Pfam: PF05103. | 0.851 |
| EFG48197.1 | crgA | HMPREF0183_0454 | HMPREF0183_2241 | Hypothetical protein. | Hypothetical protein; Involved in cell division; Belongs to the CrgA family. | 0.848 |
| EFG48197.1 | ftsZ | HMPREF0183_0454 | HMPREF0183_0455 | Hypothetical protein. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.941 |