STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG48263.1TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (382 aa)    
Predicted Functional Partners:
EFG48264.1
Putative dGTPase; COG: COG0232; Pfam: PF01966; InterPro: IPR006261; Belongs to the dGTPase family. Type 2 subfamily.
       0.828
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
    0.804
EFG47478.1
NADP oxidoreductase coenzyme F420-dependent; COG: COG5495; Pfam: PF03807.
  
    0.683
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
     0.654
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
   
 
 0.604
EFG48260.1
ABC-2 type transporter; Pfam: PF01061.
       0.562
EFG48261.1
Histidine kinase; COG: COG4585; Pfam: PF07730,PF02518; InterPro: IPR011712.
  
    0.555
tcsR2
Response regulator receiver domain protein; COG: COG2197; Pfam: PF00072,PF00196; InterPro: IPR001789.
  
    0.554
EFG48259.1
ABC transporter, ATP-binding protein; COG: COG1131; Pfam: PF00005; InterPro: IPR003593.
       0.542
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 
 0.509
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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