STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holADNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790. (325 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.999
holB
DNA polymerase III, delta' subunit; COG: COG0470.
 
 
 0.992
dnaE2
DNA polymerase III, alpha subunit; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805.
   
 0.989
dnaX
DNA polymerase III, subunit gamma and tau; COG: COG2812; Pfam: PF00004; InterPro: IPR012763.
   
 0.987
dnaE
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
   
 0.969
EFG47102.1
GIY-YIG catalytic domain protein; COG: COG0322; Pfam: PF00929,PF01541; InterPro: IPR006054.
    
 0.942
EFG48281.1
Putative DNA internalization competence protein ComEC/Rec2-like protein; COG: COG0658; Pfam: PF03772,PF00753; InterPro: IPR004477.
    
 0.838
EFG47376.1
Hypothetical protein.
  
     0.733
comEA
comEA protein; COG: COG1555; Pfam: PF00633; InterPro: IPR004509.
       0.715
mviN
Integral membrane protein MviN; COG: COG0728; Pfam: PF03023; InterPro: IPR004268.
 
  
 0.710
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.