STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupDNA-binding protein HU; COG: COG0776; Pfam: PF00216; InterPro: IPR000119; Belongs to the bacterial histone-like protein family. (94 aa)    
Predicted Functional Partners:
rpsN
Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
    0.710
rpmB
Ribosomal protein L28; COG: COG0227; Pfam: PF00830; InterPro: IPR001383; Belongs to the bacterial ribosomal protein bL28 family.
  
    0.706
rpmG
Ribosomal protein L33; COG: COG0267; Pfam: PF00471; InterPro: IPR001705; Belongs to the bacterial ribosomal protein bL33 family.
  
    0.693
lsr
Cell surface protein.
      
 0.668
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.645
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.632
EFG48105.1
cytoChrome c oxidase Caa3 assembly factor; COG: COG3336; Pfam: PF05425.
       0.610
relA
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
  
 0.581
mtnU
Hydrolase, carbon-nitrogen family; COG: COG0388; Pfam: PF00795; InterPro: IPR003010.
 
     0.570
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.569
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.