| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG48009.1 | gpmB | HMPREF0183_0697 | HMPREF0183_0698 | Glycosyltransferase, group 1 family protein; Pfam: PF00534. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078. | 0.774 |
| EFG48009.1 | nadD | HMPREF0183_0697 | HMPREF0183_0701 | Glycosyltransferase, group 1 family protein; Pfam: PF00534. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.757 |
| EFG48009.1 | rsfS | HMPREF0183_0697 | HMPREF0183_0699 | Glycosyltransferase, group 1 family protein; Pfam: PF00534. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.773 |
| eno | fbaA | HMPREF0183_2331 | HMPREF0183_1399 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.987 |
| eno | gpm | HMPREF0183_2331 | HMPREF0183_0184 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.976 |
| eno | gpmB | HMPREF0183_2331 | HMPREF0183_0698 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078. | 0.862 |
| eno | pgk | HMPREF0183_2331 | HMPREF0183_1004 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.998 |
| eno | tal | HMPREF0183_2331 | HMPREF0183_1000 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.982 |
| eno | tkt | HMPREF0183_2331 | HMPREF0183_0999 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.973 |
| fbaA | eno | HMPREF0183_1399 | HMPREF0183_2331 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.987 |
| fbaA | gpm | HMPREF0183_1399 | HMPREF0183_0184 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.961 |
| fbaA | gpmB | HMPREF0183_1399 | HMPREF0183_0698 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078. | 0.861 |
| fbaA | pgk | HMPREF0183_1399 | HMPREF0183_1004 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.992 |
| fbaA | tal | HMPREF0183_1399 | HMPREF0183_1000 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.965 |
| fbaA | tkt | HMPREF0183_1399 | HMPREF0183_0999 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.957 |
| gpm | eno | HMPREF0183_0184 | HMPREF0183_2331 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.976 |
| gpm | fbaA | HMPREF0183_0184 | HMPREF0183_1399 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.961 |
| gpm | gpmB | HMPREF0183_0184 | HMPREF0183_0698 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078. | 0.888 |
| gpm | pgk | HMPREF0183_0184 | HMPREF0183_1004 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.984 |
| gpm | serA | HMPREF0183_0184 | HMPREF0183_0100 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate dehydrogenase; COG: COG0111; Pfam: PF00389,PF02826,PF01842; InterPro: IPR006236; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.893 |