STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG47802.1Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (382 aa)    
Predicted Functional Partners:
glsA
COG: COG2066; Pfam: PF04960,PF01740; InterPro: IPR015868; Belongs to the glutaminase family.
   
 
  0.888
EFG46497.1
Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF01619,PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family.
   
 
  0.887
EFG46632.1
Amidohydrolase; COG: COG1473; Pfam: PF01546; InterPro: IPR010168.
    
  0.788
pafA
Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
      
 0.671
sseA
Rhodanese-like protein; COG: COG2897; Pfam: PF00581; InterPro: IPR001763.
       0.639
EFG47322.1
Hypothetical protein.
  
  
  0.601
nagZ
Glycosyl hydrolase family 3 N-terminal domain protein; COG: COG1472; Pfam: PF00933; InterPro: IPR001764.
       0.470
EFG46669.1
Hypothetical protein; COG: COG0493; 1.18.1.2.
  
  
  0.454
gatB
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
      
 0.428
EFG47070.1
Proteasome accessory factor PafA2; Pfam: PF03316,PF03136; InterPro: IPR004347.
      
 0.414
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.