STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG47808.1Peptidase, M48 family; Pfam: PF01435. (269 aa)    
Predicted Functional Partners:
EFG47809.1
Transcriptional regulator, BlaI/MecI/CopY family; Pfam: PF03965; InterPro: IPR005650.
 
 
  0.963
opuD2
Transporter, betaine/carnitine/choline family; COG: COG1292; Pfam: PF02028; InterPro: IPR000060; Belongs to the BCCT transporter (TC 2.A.15) family.
       0.610
EFG48493.1
Hypothetical protein.
  
     0.554
EFG46862.1
GtrA-like protein; COG: COG2246; Pfam: PF04138; InterPro: IPR007267.
  
     0.525
EFG47259.1
GtrA-like protein; COG: COG2246; Pfam: PF04138; InterPro: IPR007267.
  
     0.524
EFG46682.1
Hypothetical protein; COG: COG1985; Pfam: PF01872; InterPro: IPR002734.
  
    0.438
EFG47811.1
Transcriptional regulator, ArsR family; COG: COG0640.
       0.424
EFG47812.1
Transporter, major facilitator family protein; Pfam: PF07690; InterPro: IPR011701.
       0.424
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.408
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.