| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG47836.1 | cdd | HMPREF0183_0913 | HMPREF0183_0909 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | 0.551 |
| EFG47836.1 | deoC | HMPREF0183_0913 | HMPREF0183_0911 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.930 |
| EFG47836.1 | fbaA | HMPREF0183_0913 | HMPREF0183_1399 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.781 |
| EFG47836.1 | pgi | HMPREF0183_0913 | HMPREF0183_1001 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | Putative glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.761 |
| EFG47836.1 | rbsK | HMPREF0183_0913 | HMPREF0183_2043 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.756 |
| cdd | EFG47836.1 | HMPREF0183_0909 | HMPREF0183_0913 | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | 0.551 |
| cdd | deoA | HMPREF0183_0909 | HMPREF0183_0910 | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | Thymidine phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053. | 0.999 |
| cdd | deoC | HMPREF0183_0909 | HMPREF0183_0911 | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.892 |
| cdd | gap-2 | HMPREF0183_0909 | HMPREF0183_1005 | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.437 |
| cdd | rbsK | HMPREF0183_0909 | HMPREF0183_2043 | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.454 |
| deoA | cdd | HMPREF0183_0910 | HMPREF0183_0909 | Thymidine phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053. | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | 0.999 |
| deoA | deoC | HMPREF0183_0910 | HMPREF0183_0911 | Thymidine phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.950 |
| deoC | EFG47836.1 | HMPREF0183_0911 | HMPREF0183_0913 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055. | 0.930 |
| deoC | cdd | HMPREF0183_0911 | HMPREF0183_0909 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262. | 0.892 |
| deoC | deoA | HMPREF0183_0911 | HMPREF0183_0910 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Thymidine phosphorylase; COG: COG0213; Pfam: PF02885,PF00591,PF07831; InterPro: IPR000053. | 0.950 |
| deoC | fbaA | HMPREF0183_0911 | HMPREF0183_1399 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.895 |
| deoC | gap-2 | HMPREF0183_0911 | HMPREF0183_1005 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.896 |
| deoC | pgi | HMPREF0183_0911 | HMPREF0183_1001 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Putative glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.895 |
| deoC | rbsK | HMPREF0183_0911 | HMPREF0183_2043 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.957 |
| deoC | tal | HMPREF0183_0911 | HMPREF0183_1000 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.894 |