STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqoMalate dehydrogenase (quinone); COG: COG0579; Pfam: PF06039; InterPro: IPR006231. (496 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.972
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
    
 0.939
EFG46757.1
Hypothetical protein; COG: COG1951; Pfam: PF05681; InterPro: IPR004646; 4.2.1.2.
     
 0.918
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.917
pckA
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.903
gdhA
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.892
argH
Argininosuccinate lyase; COG: COG0165; Pfam: PF00206; InterPro: IPR009049.
    
 0.889
gltA
2-methylcitrate synthase/citrate synthase II; COG: COG0372; Pfam: PF00285; InterPro: IPR002020; Belongs to the citrate synthase family.
   
 
 0.870
gltA-2
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family.
   
 
 0.870
EFG48367.1
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
   
 
  0.757
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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