STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG47436.1Putative DEAH-box helicase; COG: COG1205; Pfam: PF00270,PF00271; InterPro: IPR014001. (759 aa)    
Predicted Functional Partners:
EFG47437.1
Methyltransferase, HemK family; Pfam: PF08241; Belongs to the methyltransferase superfamily.
       0.628
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.606
EFG48046.1
R3H domain protein; COG: COG1847; Pfam: PF01424; InterPro: IPR001374.
  
   
 0.495
EFG47025.1
Hypothetical protein; COG: COG1837; Pfam: PF00013; Belongs to the UPF0109 family.
  
   
 0.495
tnp
Integrase core domain protein; Pfam: PF00665; InterPro: IPR001584.
       0.401
EFG47433.1
ABC-2 type transporter; Pfam: PF01061; InterPro: IPR013525.
       0.401
EFG47434.1
ABC transporter, ATP-binding protein; COG: COG1131; Pfam: PF00005; InterPro: IPR003593.
       0.401
EFG47435.1
Transcriptional regulator, AbrB family; Pfam: PF04014; InterPro: IPR006339.
       0.401
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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