STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG46901.1CBS domain protein; COG: COG1253; Pfam: PF01595,PF00571,PF03471; InterPro: IPR000644. (425 aa)    
Predicted Functional Partners:
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
    0.891
EFG46899.1
PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714.
  
    0.849
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.841
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.831
EFG46903.1
ATPase, AFG1 family; COG: COG1485; Pfam: PF03969; InterPro: IPR005654.
       0.705
ppk
Polyphosphate:nucleotide phosphotransferase, PPK2 family; COG: COG2326; Pfam: PF03976; InterPro: IPR005660.
       0.705
EFG46898.1
RNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.682
dnaJ2
DnaJ domain protein; COG: COG0484; Pfam: PF01556; InterPro: IPR002939.
       0.636
rrmJ
Hemolysin TlyA family protein; COG: COG1189; Pfam: PF01479,PF08241; InterPro: IPR004538.
     
 0.434
EFG48044.1
Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
     
 0.421
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.