STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhAGlu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa)    
Predicted Functional Partners:
yerD
Glutamate synthase domain protein; COG: COG0069; Pfam: PF01645; InterPro: IPR013785; Belongs to the glutamate synthase family.
  
 0.984
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00198,PF00676,PF02779; InterPro: IPR011603.
  
 0.958
EFG46497.1
Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF01619,PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family.
  
 0.951
glnA
Glutamine synthetase, type I; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809; Belongs to the glutamine synthetase family.
  
 
 0.936
glnA2
Glutamine synthetase, beta-grasp domain protein; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR014746.
  
 
 0.929
gcvP
Glycine dehydrogenase; COG: COG1003; Pfam: PF02347,PF01212; InterPro: IPR003437; Belongs to the GcvP family.
   
 0.926
glnA-2
Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family.
  
 
 0.926
gdh
Bacterial NAD-glutamate dehydrogenase; COG: COG2902; Pfam: PF05088; InterPro: IPR007780.
     
 0.912
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
   
 
 0.911
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.905
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.