STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG46558.1Hypothetical protein; Pfam: PF02911; 2.1.2.9. (71 aa)    
Predicted Functional Partners:
EFG46557.1
Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Pfam: PF01029,PF01189; InterPro: IPR001678; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.917
rpe
Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.796
pnuC
Nicotinamide mononucleotide transporter PnuC; Pfam: PF04973.
  
    0.781
hisE-2
phosphoribosyl-ATP diphosphatase; Pfam: PF01503.
       0.779
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.768
EFG46552.1
Hypothetical protein.
    
  0.750
accD
Putative acetyl-CoA carboxylase, carboxyl transferase, beta subunit; COG: COG0777; Pfam: PF01039; InterPro: IPR000022.
       0.736
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.720
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
       0.719
EFG46546.1
Tryptophan-associated transmembrane protein (Trp_oprn_chp).
       0.713
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.