STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG46462.15'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. (754 aa)    
Predicted Functional Partners:
EFG48709.1
Endonuclease/exonuclease/phosphatase family protein; COG: COG2374; Pfam: PF04886,PF03372; InterPro: IPR005135.
  
  0.981
add-2
Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR001365.
 
  
  0.948
EFG48508.1
LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family.
 
  
 
0.947
guaB-2
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.945
punA
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.941
add
Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR001365.
    
  0.940
ushA
LPXTG-motif cell wall anchor domain protein; COG: COG0737; Pfam: PF00149,PF02872,PF00746; InterPro: IPR006179.
 
  
0.938
cdd
Cytidine deaminase; COG: COG0295; Pfam: PF00383; InterPro: IPR006262.
 
  
  0.904
guaB3
IMP dehydrogenase family protein; COG: COG0516; Pfam: PF00478; InterPro: IPR001093.
    
  0.893
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.893
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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