STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepN-2Membrane alanyl aminopeptidase; COG: COG0308; Pfam: PF01433; InterPro: IPR012778. (883 aa)    
Predicted Functional Partners:
pepA
Cytosol aminopeptidase family, catalytic domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.778
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.769
EFG46404.1
Transporter, small conductance mechanosensitive ion channel MscS family protein; COG: COG0668; Pfam: PF00924; InterPro: IPR006685.
  
    0.753
EFG46405.1
Protozoan/cyanobacterial globin family protein; COG: COG2346; Pfam: PF01152; InterPro: IPR012292.
       0.752
cysK
Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.734
EFG48367.1
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
   
 
  0.716
EFG46632.1
Amidohydrolase; COG: COG1473; Pfam: PF01546; InterPro: IPR010168.
   
 
  0.704
aspB2
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
   
 
  0.633
aspC
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
   
 
  0.633
EFG46402.1
Hypothetical protein.
       0.601
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.