STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFG46296.1Non-ribosomal peptide synthetase C-terminal domain protein; COG: COG1020; Pfam: PF00501,PF00550,PF00132; InterPro: IPR012728. (1289 aa)    
Predicted Functional Partners:
acp
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.993
pepN2
Peptidase family M1; COG: COG0308; Pfam: PF01433; InterPro: IPR014782.
 
  
  0.957
EFG46793.1
AMP-binding enzyme; Pfam: PF00561,PF00501; InterPro: IPR000873.
 
 0.929
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001; Pfam: PF00202; InterPro: IPR004639.
  
 0.900
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.898
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 
 0.895
EFG47936.1
Oxidoreductase, 2OG-Fe(II) oxygenase family protein; COG: COG3491; Pfam: PF03171; InterPro: IPR005123; Belongs to the iron/ascorbate-dependent oxidoreductase family.
  
  
 0.891
EFG46295.1
4'-phosphopantetheinyl transferase family protein; Pfam: PF01648; Belongs to the P-Pant transferase superfamily.
  
 
 0.887
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.886
fabD
Putative [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227.
 
 
 0.870
Your Current Organism:
Brevibacterium mcbrellneri
NCBI taxonomy Id: 585530
Other names: B. mcbrellneri ATCC 49030, Brevibacterium mcbrellneri ATCC 49030, Brevibacterium mcbrellneri str. ATCC 49030, Brevibacterium mcbrellneri strain ATCC 49030
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