| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFG46364.1 | cmk | HMPREF0183_2333 | HMPREF0183_2415 | MazG nucleotide pyrophosphohydrolase domain protein; COG: COG1694; Pfam: PF03819; InterPro: IPR004518. | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 0.904 |
| aroA | cmk | HMPREF0183_0338 | HMPREF0183_2415 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 0.933 |
| aroA | tyrA | HMPREF0183_0338 | HMPREF0183_2416 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydrogenase; COG: COG0287; Pfam: PF02153,PF01842; InterPro: IPR003099. | 0.825 |
| cmk | EFG46364.1 | HMPREF0183_2415 | HMPREF0183_2333 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | MazG nucleotide pyrophosphohydrolase domain protein; COG: COG1694; Pfam: PF03819; InterPro: IPR004518. | 0.904 |
| cmk | aroA | HMPREF0183_2415 | HMPREF0183_0338 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.933 |
| cmk | der | HMPREF0183_2415 | HMPREF0183_2414 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.998 |
| cmk | ndk | HMPREF0183_2415 | HMPREF0183_0712 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.953 |
| cmk | nrdF | HMPREF0183_2415 | HMPREF0183_0954 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.903 |
| cmk | rluB | HMPREF0183_2415 | HMPREF0183_2417 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.992 |
| cmk | rpsA | HMPREF0183_2415 | HMPREF0183_1018 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 30S ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | 0.921 |
| cmk | scpA | HMPREF0183_2415 | HMPREF0183_2419 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.942 |
| cmk | scpB | HMPREF0183_2415 | HMPREF0183_2418 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.963 |
| cmk | tyrA | HMPREF0183_2415 | HMPREF0183_2416 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Prephenate dehydrogenase; COG: COG0287; Pfam: PF02153,PF01842; InterPro: IPR003099. | 0.972 |
| der | cmk | HMPREF0183_2414 | HMPREF0183_2415 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 0.998 |
| der | rluB | HMPREF0183_2414 | HMPREF0183_2417 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.978 |
| der | scpA | HMPREF0183_2414 | HMPREF0183_2419 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.856 |
| der | scpB | HMPREF0183_2414 | HMPREF0183_2418 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.926 |
| der | tyrA | HMPREF0183_2414 | HMPREF0183_2416 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Prephenate dehydrogenase; COG: COG0287; Pfam: PF02153,PF01842; InterPro: IPR003099. | 0.864 |
| ndk | cmk | HMPREF0183_0712 | HMPREF0183_2415 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 0.953 |
| ndk | nrdF | HMPREF0183_0712 | HMPREF0183_0954 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.896 |