STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0CEE8_PARTEHD domain-containing protein. (481 aa)    
Predicted Functional Partners:
A0C548_PARTE
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 
 0.634
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
     
 0.601
A0DPT1_PARTE
HD domain-containing protein.
      
 0.568
A0BLQ4_PARTE
dNK domain-containing protein.
   
 
 0.559
A0BYN0_PARTE
dNK domain-containing protein.
   
 
 0.559
A0BYP7_PARTE
dNK domain-containing protein.
   
 
 0.559
A0CT58_PARTE
dNK domain-containing protein.
   
 
 0.559
A0CT82_PARTE
dNK domain-containing protein.
   
 
 0.559
A0DIK8_PARTE
dNK domain-containing protein.
   
 
 0.559
A0DRR8_PARTE
dNK domain-containing protein.
   
 
 0.559
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
Server load: low (24%) [HD]