STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0CU43_PARTECytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (144 aa)    
Predicted Functional Partners:
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
  
 
 0.879
A0C5R8_PARTE
G domain-containing protein.
  
  
 0.875
A0DI26_PARTE
G domain-containing protein.
  
  
 0.875
A0CI69_PARTE
Thymidylate_kin domain-containing protein.
    
 0.841
A0CKK9_PARTE
Thymidylate_kin domain-containing protein.
    
 0.841
A0CME0_PARTE
AA_TRNA_LIGASE_II domain-containing protein.
  
    0.791
A0D379_PARTE
AA_TRNA_LIGASE_II domain-containing protein.
  
    0.791
A0BF49_PARTE
Thymidine kinase.
    
 0.775
A0C3Z8_PARTE
Thymidine kinase.
    
 0.775
A0CA73_PARTE
Thymidine kinase.
    
 0.775
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.