STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
taw3Protein of unknown function DUF207; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (183 aa)    
Predicted Functional Partners:
taw1
Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
  
 0.853
Ferp_0739
PFAM: branched-chain amino acid transport; KEGG: dau:Daud_0349 branched-chain amino acid transport.
       0.746
Ferp_0740
PFAM: AzlC family protein; KEGG: dsa:Desal_3216 AzlC family protein.
       0.746
Ferp_1641
SMART: Nucleotide binding protein PINc; KEGG: afu:AF0591 hypothetical protein.
   
    0.597
Ferp_0741
PFAM: HEPN domain protein; SMART: HEPN domain protein; KEGG: tne:Tneu_0507 HEPN domain-containing protein.
       0.533
Ferp_0742
PFAM: DNA polymerase beta domain protein region; KEGG: afu:AF0614 hypothetical protein.
       0.533
taw2
Protein of unknown function Met10; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).
 
  
 0.500
Ferp_2260
PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: sto:ST0172 hypothetical protein.
  
     0.495
Ferp_1308
Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
 
     0.420
Ferp_0067
PFAM: protein of unknown function Met10; KEGG: afu:AF0704 hypothetical protein.
 
  
 0.414
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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