STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (210 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
 0.999
Ferp_0914
KH-domain/beta-lactamase-domain protein; KEGG: afu:AF0482 mRNA 3'-end processing factor, putative; TIGRFAM: KH-domain/beta-lactamase-domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; K Homology, type 1, subgroup; SMART: KH domain protein.
     
 0.846
Ferp_0703
PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: tsi:TSIB_0762 predicted metalloprotease.
   
 0.842
Ferp_1670
KEGG: afu:AF2198 hypothetical protein.
   
 0.842
rpl40e
KEGG: afu:AF1430 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.840
Ferp_0917
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: afu:AF0116 uroporphyrinogen III synthase (HemD).
  
  
 0.799
Ferp_0915
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: afu:AF2253 molybdopterin-guanine dinucleotide biosynthesis protein B (MobB).
       0.797
rpl10e
TIGRFAM: ribosomal protein L10.e; PFAM: Ribosomal protein L10e/L16; KEGG: afu:AF1339 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
 
  
 0.787
Ferp_0916
KEGG: afu:AF2262 hypothetical protein.
       0.773
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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