STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hepDConserved hypothetical protein; Non-heme-dependent dioxygenase that catalyzes the conversion of 2-hydroxyethylphosphonate (HEP) to hydroxymethylphosphonate (HMP) in the biosynthesis of phosphinothricin tripeptide (PTT). PTT contains the unusual amino acid phosphinothricin attached to 2 alanine residues. Synthetic phosphinothricin (glufosinate) is a key component of commercial herbicides. (443 aa)    
Predicted Functional Partners:
phpC
Conserved hypothetical protein; Catalyzes the reduction of phosphonoacetaldehyde to 2- hydroxyethylphosphonate, a step in the biosynthesis of phosphinothricin tripeptide. Phosphinothricin tripeptide is both a natural-product antibiotic and potent herbicide. Can use both NAD and NADP but the preferred substrate is NAD.
    
 0.951
EFL30522.1
Conserved hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.879
ppd
Phosphonopyruvate decarboxylase.
       0.667
ppm
Phosphonopyruvate hydrolase; Formation of a carbon-phosphorus bond by converting phosphoenolpyruvate (PEP) to phosphonopyruvate (P-Pyr).
       0.637
EFL30519.1
Conserved hypothetical protein.
       0.629
EFL30525.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
       0.603
EFL30517.1
Phosphopyruvate hydratase.
       0.499
EFL30518.1
Conserved hypothetical protein.
       0.499
EFL30526.1
Phosphinothricin tripeptide synthetase II.
       0.475
Your Current Organism:
Streptomyces viridochromogenes
NCBI taxonomy Id: 591159
Other names: S. viridochromogenes DSM 40736, Streptomyces viridochromogenes DSM 40736, Streptomyces viridochromogenes str. DSM 40736, Streptomyces viridochromogenes strain DSM 40736
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.