STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_2282PFAM: aminotransferase class I and II; KEGG: sgr:SGR_2554 aminotransferase AlaT. (403 aa)    
Predicted Functional Partners:
ilvD
TIGRFAM: dihydroxy-acid dehydratase; KEGG: sgr:SGR_4135 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.914
Sfla_3735
KEGG: rha:RHA1_ro04990 ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin.
    
 0.909
Sfla_5047
TIGRFAM: alanine dehydrogenase; KEGG: sgr:SGR_5724 putative L-alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein.
     
 0.909
Sfla_1812
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; KEGG: sgr:SGR_1979 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.908
Sfla_1815
TIGRFAM: branched-chain amino acid aminotransferase; KEGG: sgr:SGR_1982 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV.
  
 
 0.908
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.908
Sfla_5293
PFAM: aminotransferase class IV; KEGG: sgr:SGR_5991 putative aminotransferase.
  
 
 0.908
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.907
Sfla_0626
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sma:SAV_1636 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.907
Sfla_2319
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sgr:SGR_2604 glutamate dehydrogenase; SMART: Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.907
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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