STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_2479Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (411 aa)    
Predicted Functional Partners:
ddl
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.987
Sfla_2477
PFAM: Uncharacterised protein family UPF0079, ATPase; KEGG: sgr:SGR_2784 hypothetical protein.
  
 0.987
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.977
Sfla_5047
TIGRFAM: alanine dehydrogenase; KEGG: sgr:SGR_5724 putative L-alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein.
  
 
 0.962
Sfla_0105
Amino acid adenylation domain protein; KEGG: fal:FRAAL2542 non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.951
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
  
  
 0.850
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.821
Sfla_2282
PFAM: aminotransferase class I and II; KEGG: sgr:SGR_2554 aminotransferase AlaT.
    
 0.818
Sfla_4847
PFAM: aminotransferase class I and II; KEGG: sgr:SGR_5548 aminotransferase AlaT.
    
 0.818
Sfla_3735
KEGG: rha:RHA1_ro04990 ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin.
     
 0.817
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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