STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_3194PFAM: Rhomboid family protein; KEGG: sgr:SGR_3717 hypothetical protein. (300 aa)    
Predicted Functional Partners:
Sfla_4679
PFAM: Rhomboid family protein; KEGG: sgr:SGR_5364 putative integral membrane protein.
  
   
 0.782
Sfla_3193
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.742
Sfla_4820
Response regulator receiver and ANTAR domain protein; KEGG: sgr:SGR_5518 putative two-component system response regulator; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver.
      
 0.671
Sfla_3192
KEGG: sgr:SGR_3715 putative regulatory protein.
  
    0.630
Sfla_4516
KEGG: sgr:SGR_5195 hypothetical protein; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin.
  
   0.630
Sfla_3702
KEGG: scb:SCAB_53121 putative 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.452
Sfla_3605
PFAM: Rhomboid family protein; KEGG: sgr:SGR_4203 hypothetical protein.
      
0.416
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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