STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_3892PFAM: Glycerophosphoryl diester phosphodiesterase, membrane domain; KEGG: sgr:SGR_4521 putative integral membrane protein. (399 aa)    
Predicted Functional Partners:
Sfla_3890
KEGG: sgr:SGR_4519 putative secreted protein.
 
     0.966
Sfla_3888
KEGG: sgr:SGR_4517 hypothetical protein; PFAM: protein of unknown function DUF58; SMART: von Willebrand factor type A.
 
     0.965
Sfla_3891
KEGG: sgr:SGR_4520 putative integral membrane protein.
 
     0.965
Sfla_3889
KEGG: sgr:SGR_4518 putative regulatory protein; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase.
 
     0.901
Sfla_3886
PFAM: RDD domain containing protein; KEGG: sgr:SGR_4515 hypothetical protein.
 
     0.771
Sfla_3887
PFAM: protein of unknown function DUF95 transmembrane; KEGG: sgr:SGR_4516 hypothetical protein.
 
     0.769
Sfla_3893
TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; KEGG: sgr:SGR_4522 putative methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family.
       0.732
Sfla_3894
Two component transcriptional regulator, winged helix family; KEGG: sgr:SGR_4523 putative two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
       0.720
Sfla_3895
Integral membrane sensor signal transduction histidine kinase; KEGG: sgr:SGR_4524 putative two-component system sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
       0.720
lpqB
PFAM: Lipoprotein LpqB, beta-propeller domain-like; Lipoprotein LpqB, GerMN domain; KEGG: sgr:SGR_4525 lipoprotein LpqB.
       0.698
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.