node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT34437.1 | KRT34438.1 | HMPREF1705_04658 | HMPREF1705_04632 | Hypothetical protein. | Magnesium transporter; Acts as a magnesium transporter. | 0.472 |
KRT34437.1 | KRT34439.1 | HMPREF1705_04658 | HMPREF1705_04643 | Hypothetical protein. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.445 |
KRT34438.1 | KRT34437.1 | HMPREF1705_04632 | HMPREF1705_04658 | Magnesium transporter; Acts as a magnesium transporter. | Hypothetical protein. | 0.472 |
KRT34438.1 | KRT34439.1 | HMPREF1705_04632 | HMPREF1705_04643 | Magnesium transporter; Acts as a magnesium transporter. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.723 |
KRT34438.1 | KRT34885.1 | HMPREF1705_04632 | HMPREF1705_04135 | Magnesium transporter; Acts as a magnesium transporter. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.474 |
KRT34438.1 | KRT35664.1 | HMPREF1705_04632 | HMPREF1705_02906 | Magnesium transporter; Acts as a magnesium transporter. | Putative arabinose 5-phosphate isomerase; KEGG: aco:Amico_1493 2.1e-105 KpsF/GutQ family protein K06041; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.535 |
KRT34438.1 | KRT36190.1 | HMPREF1705_04632 | HMPREF1705_03458 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: aco:Amico_0778 4.7e-60 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.452 |
KRT34438.1 | KRT36227.1 | HMPREF1705_04632 | HMPREF1705_03495 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: bca:BCE_0044 1.2e-38 purR; pur operon repressor K09685; Psort location: Cytoplasmic, score: 8.96. | 0.435 |
KRT34438.1 | guaA | HMPREF1705_04632 | HMPREF1705_04024 | Magnesium transporter; Acts as a magnesium transporter. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.915 |
KRT34438.1 | guaB | HMPREF1705_04632 | HMPREF1705_03444 | Magnesium transporter; Acts as a magnesium transporter. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.833 |
KRT34438.1 | purA | HMPREF1705_04632 | HMPREF1705_03154 | Magnesium transporter; Acts as a magnesium transporter. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.519 |
KRT34438.1 | purH | HMPREF1705_04632 | HMPREF1705_03299 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: aco:Amico_1169 4.8e-145 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 9.97. | 0.500 |
KRT34439.1 | KRT34437.1 | HMPREF1705_04643 | HMPREF1705_04658 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | Hypothetical protein. | 0.445 |
KRT34439.1 | KRT34438.1 | HMPREF1705_04643 | HMPREF1705_04632 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | Magnesium transporter; Acts as a magnesium transporter. | 0.723 |
KRT34885.1 | KRT34438.1 | HMPREF1705_04135 | HMPREF1705_04632 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.474 |
KRT34885.1 | KRT36190.1 | HMPREF1705_04135 | HMPREF1705_03458 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: aco:Amico_0778 4.7e-60 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.851 |
KRT34885.1 | KRT36227.1 | HMPREF1705_04135 | HMPREF1705_03495 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: bca:BCE_0044 1.2e-38 purR; pur operon repressor K09685; Psort location: Cytoplasmic, score: 8.96. | 0.487 |
KRT34885.1 | guaA | HMPREF1705_04135 | HMPREF1705_04024 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.978 |
KRT34885.1 | guaB | HMPREF1705_04135 | HMPREF1705_03444 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.953 |
KRT34885.1 | purA | HMPREF1705_04135 | HMPREF1705_03154 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.731 |