STRINGSTRING
murD protein (Dialister invisus) - STRING interaction network
"murD" - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase in Dialister invisus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase ; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (456 aa)    
Predicted Functional Partners:
murC
UDP-N-acetylmuramoyl-L-alanine synthetase ; Cell wall formation (469 aa)
 
  0.999
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase (499 aa)
 
 
  0.999
murI
Glutamate racemase ; Provides the (R)-glutamate required for cell wall biosynthesis (258 aa)
 
 
  0.996
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase ; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (371 aa)
 
 
  0.994
ddl
D-alanylalanine synthetase ; Cell wall formation (311 aa)
 
  0.992
mraY
UDP-MurNAc-pentapeptide phosphotransferase ; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (320 aa)
 
   
  0.981
murF
D-alanyl-D-alanine-adding enzyme ; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (459 aa)
 
 
0.974
GCWU000321_00354
UDP-N-acetylmuramate dehydrogenase ; Cell wall formation (301 aa)
 
 
  0.941
murA
UDP-N-acetylglucosamine enolpyruvyl transferase ; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (404 aa)
 
 
  0.940
ftsZ
Cell division protein FtsZ ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (360 aa)
   
 
  0.923
Your Current Organism:
Dialister invisus
NCBI taxonomy Id: 592028
Other names: D. invisus, D. invisus DSM 15470, Dialister invisus, Dialister invisus DSM 15470, Dialister invisus Downes et al. 2003, Dialister invisus str. DSM 15470, Dialister invisus strain DSM 15470
Server load: low (10%) [HD]