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GCWU000321_00160 protein (Dialister invisus) - STRING interaction network
"GCWU000321_00160" - ATPase family associated with various cellular activities in Dialister invisus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GCWU000321_00160ATPase family associated with various cellular activities (AAA) (801 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (404 aa)
   
  0.983
dnaK
Heat shock protein 70 ; Acts as a chaperone (620 aa)
   
 
  0.979
grpE
HSP-70 cofactor ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depend [...] (200 aa)
   
 
  0.967
clpP
Endopeptidase Clp ; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (207 aa)
   
 
  0.963
ctsR
Transcriptional regulator CtsR (163 aa)
         
  0.942
hrcA
Heat-inducible transcription repressor HrcA ; Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (360 aa)
   
   
  0.867
GCWU000321_00159
Uncharacterized protein (163 aa)
 
   
  0.861
groS
Protein Cpn10 ; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (102 aa)
   
 
  0.858
groL
Protein Cpn60 ; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (540 aa)
   
 
  0.855
radA
DNA repair protein radA ; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (466 aa)
 
     
  0.829
Your Current Organism:
Dialister invisus
NCBI taxonomy Id: 592028
Other names: D. invisus, D. invisus DSM 15470, Dialister invisus, Dialister invisus DSM 15470, Dialister invisus Downes et al. 2003, Dialister invisus str. DSM 15470, Dialister invisus strain DSM 15470
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