STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEW96436.1Phosphoribulokinase/uridine kinase family protein; KEGG: ctc:CTC00344 6.7e-103 uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96. (549 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.974
EEW97333.1
5'-nucleotidase, C-terminal domain protein; KEGG: tma:TM1878 5.3e-55 UDP-sugar hydrolase K01081:K08077; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family.
  
 
 0.967
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.930
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.929
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.919
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.916
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: ban:BA5369 1.1e-109 gap-2; glyceraldehyde 3-phosphate dehydrogenase K00134; Psort location: Cytoplasmic, score: 9.97; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.916
cmk
Cytidylate kinase; KEGG: bli:BL02219 2.3e-52 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.895
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
 0.886
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.882
Your Current Organism:
Dialister invisus
NCBI taxonomy Id: 592028
Other names: D. invisus DSM 15470, Dialister invisus DSM 15470, Dialister invisus str. DSM 15470, Dialister invisus strain DSM 15470
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