STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (471 aa)    
Predicted Functional Partners:
EEW97963.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952.
 
 0.998
purD
KEGG: csa:Csal_0909 5.9e-111 phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 8.96; Belongs to the GARS family.
 
 0.996
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.0e-94 phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 8.96.
 
 0.996
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 0.984
purH
KEGG: gka:GK0267 1.6e-156 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602:K01492; Psort location: Cytoplasmic, score: 8.96.
 
 0.983
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.983
purC
KEGG: gsu:GSU2091 7.8e-77 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family.
  
 0.965
carB
KEGG: chy:CHY_1499 0. carB; carbamoyl-phosphate synthase, large subunit K01955; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarB family.
  
 
 0.870
carA
KEGG: mta:Moth_0881 3.3e-94 carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family.
  
 
 0.846
purB
Adenylosuccinate lyase; KEGG: gme:Gmet_1943 2.3e-141 adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.823
Your Current Organism:
Dialister invisus
NCBI taxonomy Id: 592028
Other names: D. invisus DSM 15470, Dialister invisus DSM 15470, Dialister invisus str. DSM 15470, Dialister invisus strain DSM 15470
Server load: low (32%) [HD]